- PII
- 10.31857/S0044460X23040042-1
- DOI
- 10.31857/S0044460X23040042
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 93 / Issue number 4
- Pages
- 525-530
- Abstract
- Reaction of 3-diethylamino-1-aryl-, 3-diethylamino-1-aryl-2-phenyl(4-halophenyl)propane-1-ones hydrochlorides with 6-amino-1,3-dimethyluracil results in heterocyclization products, namely 1,3-dimethyl-7-aryl-5,6dihydro-1 H -pyrido[2,3- d ]pyrimidine-2,4-diones, 1,3-dimethyl-7-aryl-6-phenyl(4-halophenyl)-5,6-dihydro1 H -pyrido[2,3- d ]pyrimidine-2,4-diones and 1,3-dimethyl-7-aryl-6-phenyl-(4-halophenyl)-1 H -pyrido[2,3- d ] pyrimidine-2,4-diones. The effect of the synthesized compounds in vitro tumor DNA methylation was studied.
- Keywords
- 6-амино-1,3-диметилурацил замещенныe пиридо[2,3-d]пиримидины гетероциклизация опухолевая ДНК
- Date of publication
- 15.04.2023
- Year of publication
- 2023
- Number of purchasers
- 0
- Views
- 33
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