- PII
- 10.31857/S0044460X23010122-1
- DOI
- 10.31857/S0044460X23010122
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 93 / Issue number 1
- Pages
- 106-112
- Abstract
- Triterpenoids with a pyridinylmethylidene substituent in the C2 position were prepared via the reaction of betulonic acid with pyridine-2-carbaldehyde, pyridine-3-carbaldehyde, pyridine-4-carbaldehyde or quinoline-2-carbaldehyde. The products were tested as ligands for palladium(II). Two ligands and one complex were prepared for the first time. The structures of new compounds were confirmed by 1D and 2D NMR spectra, as well as by electrospray ionization mass spectra. The E -isomerism of pyridinylmethylidene substituent in the C2 position of triterpenoid was proved. Cytotoxic activity of the complexes with respect to A549 (adenocarcinomic human alveolar basal epithelial cells) cell line was estimated.
- Keywords
- тритерпеноид комплекс палладия(II) цитотоксическая активность
- Date of publication
- 15.01.2023
- Year of publication
- 2023
- Number of purchasers
- 0
- Views
- 31
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