RAS Chemistry & Material ScienceЖурнал общей химии Russian Journal of General Chemistry

  • ISSN (Print) 0044-460X
  • ISSN (Online) 3034-5596

Search for Monoamine Oxidase Inhibitors among Pyrazoline and Pyrimidine Derivatives and Studying Luminescent Properties of the Obtained Compounds

PII
10.31857/S0044460X24010065-1
DOI
10.31857/S0044460X24010065
Publication type
Article
Status
Published
Authors
Volume/ Edition
Volume 94 / Issue number 1
Pages
80-91
Abstract
Cyclization of the (E)-3-aryl-1-(4-alkoxyphenyl)prop-2-en-1-ones with phenylhydrazine in an acidic medium leads to the 5-aryl-3-(4-alkoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazoles. Bubbling air through a solution of 5-(4-methoxyphenyl)-1-phenyl-3-(4-ethoxyphenyl)-4,5-dihydro-1H-pyrazole in ethylcellosolve resulted in an oxidation-dehydrogenation product, which characterized as the picrate of the corresponding pyrazole. The reaction of benzamidine and 4-methylbenzamidine hydrochlorides with substituted chalcones in а KOH–ethanol system leads to 2,4-diaryl-6-(4-alkoxyphenyl)pyrimidines. The luminescent and antimonoamine oxidase properties of the resulting systems were studied.
Keywords
замещенные проп-2-ен-1-оны пиразолины пикрат пиразола пиримидины люминесцентные свойства антимоноаминоксидазная активность
Date of publication
17.09.2025
Year of publication
2025
Number of purchasers
0
Views
12

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